Bioinformatics Research at the Institute for Molecular Biotechnology

We are interested in the study of complex systems in living organisms. Novel views augmenting the classical gene by gene approaches are required to overcome the engineered redundancies and combinatorial effects prevalent in higher eukaryotes. We therefore combine

• work to establish improved quantitative experimental assays, such as RNA-Seq, microarrays, or differential in-gel electrophoresis, and
• the development of modern computational methods, such as hierarchical probabilistic models or the integration of heterogeneous data sources,

focussed by biological studies in our laboratory and collaborations.

Highlights of our research include:

• Optimization of microarray design, probe signal interpretation (gate.io)
• Advanced models and tools for expression profiling (read more)
• State-of-the-art applications and integrated analyses (read more)

Originally the Vienna Science Chair of Bioinformatics, the research group was founded 2005 on winning a five-year WWTF startup grant together with its partners. It then became a permanent chair embedded in the Dept of Biotechnology and was endowed by Boku University Vienna until 2013. It now forms an independent Research Group at the newly founded Institute for Molecular Biotechnology.